Dose-Aware Cold Diffusion with Physics Consistency for Generalizable Low-Dose CT Reconstruction

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arXiv cs.AI · Md Imam Ahasan, Guangchao Yang, A F M Abdun Noor, S M Hasan Mahmud, Md Mahfuzur Rahman · 2026-09-17 AI

[Submitted on 15 Jul 2026]

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Abstract:Reducing radiation dose in computed tomography significantly degrades image quality and poses challenges for accurate and clinically reliable reconstruction. While recent approaches have shown promise for low-dose CT, they often struggle to generalize across continuous and previously unseen dose levels, leading to artifacts and loss of anatomical detail. To address these limitations, we propose Dose-Aware Cold Diffusion (DACD), a physics-consistent reconstruction framework that explicitly models radiation dose as a continuous latent factor within a cold diffusion process. The proposed DACD framework integrates image-based dose-aware perception, multi-scale structural prior extraction, and dose-calibrated step allocation to adaptively guide the denoising trajectory. In addition, an iterative forward-backprojection correction is incorporated into the reverse refinement process to enforce projection-domain data consistency. Extensive experiments on three public benchmarks, including Mayo-2020, Mayo-2016, and LoDoPaB-CT, demonstrate that DACD consistently outperforms state-of-the-art diffusion-based and physics-guided methods in both quantitative accuracy and visual fidelity, particularly under ultra-low-dose conditions. The results show that DACD achieves robust generalization across a continuous range of dose levels, including those unseen during training.

Submission history

From: Md Imam Ahasan [view email]
[v1] Wed, 15 Jul 2026 02:34:58 UTC (6,344 KB)

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추출 본문 · 출처: arxiv.org · https://arxiv.org/abs/2609.18943